How do Vaccines Protect my Cat?
Vaccines do not inject a miraculous shield against disease. They work by fooling the body into thinking it is threatened, thereby stimulating the body's own defense system into producing antibodies to fight off the invader. Vaccines are made from either killed viruses or weakened viruses (modified live - MLV), and can be given individually, although some serums are often given as a group (multivalent), e.g. the "3-Way, " or FRCP. (See page 2 for more information on multivalent vaccines.)
Vaccines are most commonly given by injection, although several new intranasal vaccines have been developed, which are recommended by the VAFSTF where available.
After the initial "kitten shots," boosters are given to boost the cat's defense system. Traditionally, veterinarians have asked owners to bring their cats in for annual boosters, along with their annual well-cat checkup, however times are changing and many veterinarians are moving to an every three year protocol, with some exceptions.
In 1996, due to increasing concerns about tumors found at the sites of certain vaccinations, a Vaccine-Associated Feline Sarcoma Task Force (VAFSTF), consisting of representatives from American Association of Feline Practitioners (AAFP), American Animal Hospital Association (AAHA), American Veterinary Medical Association (AVMA), and Veterinary Cancer Society (VCS), researchers, clinicians, and government representatives, was formed to study this phenomenon. Their published results included certain vaccines as "core" (highly recommended for all cats).
Core Vaccines:
- Feline Panleukopenia Virus Vaccine (also called "Feline Distemper")
Panleukopenia is caused by a feline parvovirus (FPV), and is particularly vicious, capable of being spread rapidly, with a high mortality rate, especially in younger cats. After a one-year booster for kittens, this vaccination can be given every three years. - Feline Calicivirus
This virus, along with the Feline Herpes virus, causes the majority of upper respiratory infections URIs in cats, and can be spread by "carrier" cats for years. This vaccine may be given at three year intervals after the initial series. - Rhinotracheitis AKA Feline Herpes Virus
Rhinotracheitis has serious potential, especially in kittens. It has been estimated that 70% of kittens with severe Rhinotracheitis infections will die, and it can also cause permanent neurological damage to kittens.NOTE: These vaccines will not provide total clinical immunity to the diseases, but will minimize the severity of upper respiratory infection.
- Rabies Vaccine
Rabies vaccinations are required by law in most states in the U.S. The interval depends on the jurisdiction, and can be from one to three years. Although the incidence of rabies in cats is relatively low, even indoor cats are at risk, as bats do enter homes. Rabies is always fatal in an unprotected cat, and both the VAFSTF and the AAFP highly recommend vaccination of all cats for this zoonotic disease.The Rabies vaccine is one which is implicated as causing vaccine-associated sarcoma (VAS), and it is suspected that the adjuvant (carrier) used may be the culprit associated with this vaccine. A new non-adjuvanted vaccine (PureVax Feline Rabies Vaccine, Merial Ltd.) is available, but its reduced likelihood of association with VAS has not yet been proved by studies. This vaccine is presently licensed only for annual administration.
Next > Live VS Killed Vaccines

